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Oct 2025 DOI 10.14302/issn.3070-3360.ijco-25-5740
Patricia Nava González LauraCorresponding author
Significance This case report describes the alternative management of hyperuricemia through acupuncture using the Luo Yuan technique. Case presentation A 53-year-old Mexican man was diagnosed with secondary hyperuricemia. The patient began to experience arthralgia in the metatarsophalangeal joint of the first toe on his left foot after consuming a high amount of purine-rich foods, with a 10-year history. The symptoms were sporadically controlled with the use of colchicine and indarzone. In a six-element blood chemistry test, serum uric acid was 8.7 mg/dL before acupuncture treatment and 8.3 mg/dL at the end of treatment, without applying dietary restrictions on purine consumption. Conclusions and relevance This report demonstrates the potential efficacy of acupuncture at the Luo and Yuan points of the Spleen and Stomach meridians in reducing elevated blood uric acid levels. This suggests its potential as an alternative treatment for patients with hyperuricemia and other metabolic disorders.
Jan 2024
Manga SeleneCorresponding author
Drug-resistant tuberculosis (DR-TB) is the most urgent public health problem to solve in Peru, according to the Ministry of Health 1. In the WHO Global TB Report 2021, Peru has the highest burden of DR-TB in the Americas (Table 1), with 38% of TB cases either RR or MDR. In addition, the Ministry reports an estimated prevalence rate of DR-TB of 5.7% in new cases and 24.2% in previously treated cases. A total of 2493 new cases of DR-TB were reported in 2022, with 18.5% treatment dropout in 2019 believed to have increased by at least 52% in 2022 1. The post-pandemic context has created additional challenges for the control of DR-TB in Peru. A complex multiplicity of factors connects this disease to groups with high vulnerability, such as populations in extreme poverty and overcrowding or deprived of freedom; those who have immune system disorders, such as HIV and diabetes; and isolated indigenous populations.
Oct 2021 DOI 10.14302/issn.2643-2811.jmbr-21-3954
Isea RaúlCorresponding author
Fundación Instituto de Estudios Avanzados, Hoyo de la Puerta, Baruta, Venezuela.
This paper performs a forensic study of the Peru’s presidential election on June 6th, 2021 between Pedro Castillo and Keiko Fujimori, where ex-candidate Keiko Fujimori claimed there had been irregularities. We calculate three p-values that help us determine if there was fraud. The consensus of the results indicates that there was no manipulation of the results.
Jun 2021 DOI 10.14302/issn.2639-3166.jar-21-3816
Elamin Elhaj WaleedCorresponding author
Department of Plant Protection, College of Agricultural Studies, Sudan University of Science and Technology, Khartoum State, Sudan.
African bollwormis a worldwide-spread species that shows a high degree of polyphagia and it is considered as one of the main agricultural pests in the world. Laboratory experiments were conducted in the Research Laboratory, College of Agricultural Studies, Sudan University of Science and Technology to evaluate the lethal effect of C. rotundusand D. stramonium on the H. armigeraand to investigate the synergistic effect of sesame oil and tested extracts by dipping methods. Five concentrations (4%, 6%, 8%, 10% and 12%) were used for each plant extract in a Completely Randomized Design. Tubers ethanolic extract of C. rotundus at 12% concentration caused 90% mortality after 72 hrs of application, whereas 12% concentration of seeds ethanolic extract of D. stramonium generate only 70% mortality after 72 hrs of exposure. When sesame oil was added to each concentration of ethanolic extract of C. rotundus and D. stramonium it exhibited a synergistic effect. In fact, the 10% concentration scored 53.3% and 76.7% mortality, however, when mixed with sesame oil the mortality increased significantly to 83.3% and 100% for D. stramonium and C. rotundus respectively after 72 hrs of exposure. This study clearly demonstrates that both tested plants have a lethal effect on the larvae of the African bollworm. However, tubers ethanolic extract of C. rotundus seems to be significantly more toxic than the seeds ethanolic extract of D. stramonium. This study also revealed that sesame oil has a synergistic effect when added to these plant extracts.
May 2021 DOI 10.14302/issn.2470-5020.jnrt-21-3843
R. Plasencia AndrésCorresponding author
Department of Neurointerventional Radiology at Clínica Internacional de San Borja, Lima, Peru
Background Perimedullary arteriovenous fistulae, or type IV spinal cord arteriovenous malformations, are very rare and not well-known lesions. This paper aims to present our endovascular experience with these lesions. Methods We report our experience with 4 patients with perimedullary arteriovenous fistulae, subtypes b and c (macrofistulae), exhibiting severe neurological impairment. The patients were treated with endovascular embolization. Results Complete fistula eradication was achieved in all of them. One complication occurred. We discuss the natural history, pathophysiology, clinical presentation, prognosis and embolization techniques, along with the angiographic and clinical outcomes. Conclusion Our experience with endovascular embolization as an upfront treatment allowed us to eradicate these lesions in a safe and effective way, arresting the clinical worsening and reversing partially or completely the neurological injury in most of our cases.
Feb 2023 DOI 10.14302/issn.2576-6694.jbbs-22-4418
Mostafa M. Sabra SherifaCorresponding author
Saudi Arabia is rich in Juniperusprocera Hochst. ex Endl (Cupressaceae) as a medicinal plant. Its known as Arar, its present southwards, KSA. It's used as traditional medicine in the southwestern, KSA. The aim was according to "Saudi Arabian Customs" in using wild-plant extract for treatment and prevention of infectious-pathogens. That was to use Juniperusprocerafrom Ranyah, KSA to eliminate infectious-pathogens that were isolated from patients in the same area. This was the use may reduce the use of chemicals, as well it may be an alternative to chemotherapy. Practice included preparation of wild-plant extract, preparation of infectious-pathogens, interaction to wild-plant extract, and direct total cell count by "Bread Test". Juniperusprocera one crude concentration killed all infectious-pathogens during one day. Lower Juniperusprocera crude extract concentrations eliminated infectious-pathogens within more than one day. The mean number of dead sells / mL of Staphylococcus sp., Streptococcus sp, and Streptococcus pyogenes were (84.9 / mL, 87.0 / mL, and 77.8 / mL). The mean percent of dead cells were (80.0%, 82.0%, and 73.4%). The meannumber of dead sells / mL of Salmonella sp., Shigella sp, and Escherichia coli were (72.6 / mL, 76.1 / mL, and 79.0 / mL). The mean percent of dead cells were (68.5%, 71.8%, and 74.5%). The mean number of Candida albicans dead sells / mL was 69.3 / mL, the mean percent of dead cells was 65.4%. It was concluded that found from the results, the Juniperusprocera extract was preferred "Saudi Arabian Customs" to be used in three quarter and one crude concentration, as the infectious-pathogens eliminating within one day. It was recommended that the Juniperusprocera extract will be used for herbal treatment according to "Saudi Arabian Customs". That will be remark and follow-up through the "Official Herbal Treatment Dept.". That will appropriate the doses will estimate for each patient to eliminate and protect against the infectious-pathogens.
Aug 2021 DOI 10.14302/issn.2692-1537.ijcv-21-3918
Isea RaúlCorresponding author
Fundación Instituto de Estudios Avanzados, Hoyo de la Puerta, Baruta, Venezuela.
Mathematical and computational studies of Covid-19 have underestimated the influence that other countries have on their daily records. To visualize this, a Granger causality analysis was implemented in Python to determine if the cases registered in Brazil, Chile, Colombia, Ecuador, Panama, Paraguay, Peru and the USA have any effect on Venezuela, and between all of them. Finally, this paper highlights the need to incorporate causality analysis employing only the cases of Covid-19 to improve mid and long term forecasts.
Jul 2020 DOI 10.14302/issn.2692-1537.ijcv-20-3453
Isea RaulCorresponding author
Fundación Instituto de Estudios Avanzados IDEA, Hoyo de la Puerta, Baruta, Venezuela
The present work analyzes the registered cases of Covid-19 throughout the world according the data registered at Johns Hopkins University. We selected 15 countries to analyze their data. In alphabetical order the countries are: Argentina, Australia, Brazil, Chile, China, Colombia, Germany, India, Italy, Mexico, Peru, Portugal, Spain, United States and Venezuela. With this information, three different studies were carried out. First, the data was validated using Benford's Law which is based on forensic techniques that allow us to guarantee the integrity of the information. Later, we calculated the value of the basic reproduction number (R0), ie., the number of secondary host infections caused by one primary host infection that helps us to determine if a country has an outbreak of Covid-19. Finally, we show that the best representation for the change in the number of cases in the time is to calculate the mantissa value, ie., the floating number obtained from the logarithm of the data.
Apr 2020 DOI 10.14302/issn.2575-7881.jdrr-20-3267
Sharma BechanCorresponding author
Department of Biochemistry, Faculty of Science, University of Allahabad, Allahabad-211002, Uttar Pradesh, India
The phytochemicals are endowed with antioxidant activities because of the presence of plentiful polyphenols and many other phytochemicals. However, some recent reports have suggested that phytochemicals from certain plant species exhibit DNA damaging properties mainly due to presence of alkaloids. In the present study, pBR322, Salmonella typhi DNA, insect DNA and human DNA were treated with hexanolic extract of Argemone mexicana and Thevesia peruviana leaves to assess their DNA damaging abilities. Another set of experiments was carried out using the methanolic extracts of Citrus lemon leaves to assess their DNA protecting abilities from damage of DNA by extracts of A. mexicana and T. peruviana at 150000 ppm for all DNAs used. The results indicated that the leaves extract of A. mexicanaand T. peruviana demonstrated significant DNA damaging potential at higher concentrations. In contrast, the extracts from C. limonat 15000 ppm showed maximum DNA protective properties for all DNAs used.
Feb 2019 DOI 10.14302/issn.2641-9467.jgrc-19-2619
Sørensen MartenCorresponding author
Department of Plant & Environmental Sciences, University of Copenhagen, Thorvaldsensvej 40, 3., 1870 Frederiksberg C.
The Andean region is the centre of origin and domestication of at least 9 species of native root and tuber crops in addition to several species of native potatoes. Within this group, Mauka – also known as Miso or Taso ‒ (Mirabilis expansa Ruíz & Pav.) Standl. ‒ Nyctaginaceae) is one of the least well known, despite having much potential. It is cultivated at high altitudes (2300 to 3500 m a.s.l.) in Ecuador, Peru and Bolivia and is thought to be of pre-Inca origin. Mauka is characterized by its high nutritional value due to substantial levels of protein, calcium and phosphorus, as well as secondary metabolites with nutraceutical properties of varied application. It also has good potential as a forage plant. Based on ethnobotanical knowledge and scientific investigations, this review presents advances in the agronomic understanding of Mauka since its discovery five decades ago in several isolated rural Bolivian communities. The information presented covers both Andean and non-Andean countries. It includes results from journals on natural resources, botany, agronomy, and the congress minutes from botanical, agronomic and phytogenetic resources conferences. Theses on Mauka specifically and on phytogenetic resources in general were also reviewed. Books and manuals were reviewed in the libraries of the International Potato Center, INIAP-Ecuador, INIA-Peru and universities. The plant is described with emphasis on its agronomic traits and according to its propagation forms (seed or vegetative); in terms of its agroecology, phenology, growth dynamics and their indices, crop management, harvest and post-harvest processes. It is concluded that important advances in the understanding of the agronomy of Mauka have been accomplished. Furthermore, the review highlights aspects requiring further research, in order to develop improved production technologies to ensure its future use and conservation.