Aims & Scope
Journal of New Developments in Molecular Biology (JNMB) publishes fundamental research on molecular mechanisms, cellular processes, and biomolecular interactions that advance our understanding of life at the molecular level.
Core Research Domains
Molecular Genetics & Genomics
Fundamental mechanisms of genetic information flow, genome organization, and regulation.
- Gene expression and transcriptional regulation
- DNA replication, repair, and recombination
- Chromatin structure and epigenetic modifications
- Genome organization and nuclear architecture
- RNA biology and post-transcriptional regulation
- Genomic technologies and sequencing methods
"Characterization of novel histone modifications regulating developmental gene expression in stem cells through ChIP-seq and functional genomics approaches."
Protein Science & Structural Biology
Molecular architecture, dynamics, and functional mechanisms of proteins and macromolecular complexes.
- Protein structure determination and modeling
- Protein folding, stability, and quality control
- Molecular chaperones and protein degradation
- Enzyme mechanisms and catalysis
- Protein-protein and protein-nucleic acid interactions
- Post-translational modifications
"Cryo-EM structure of a ribosomal quality control complex reveals molecular basis for nascent chain recognition and ubiquitination."
Cell Signaling & Regulation
Molecular pathways controlling cellular responses, communication, and homeostasis.
- Signal transduction cascades and networks
- Cell cycle regulation and checkpoints
- Cellular stress responses and adaptation
- Membrane receptors and ion channels
- Second messenger systems
- Cell-cell communication mechanisms
"Identification of feedback loops in MAPK signaling pathways using quantitative phosphoproteomics and mathematical modeling."
Cellular Organization & Dynamics
Molecular basis of cellular architecture, compartmentalization, and dynamic processes.
- Cytoskeletal organization and motor proteins
- Membrane trafficking and organelle biogenesis
- Autophagy and cellular degradation pathways
- Cell division mechanisms (mitosis, cytokinesis)
- Cell differentiation and developmental processes
- Programmed cell death (apoptosis, necrosis)
"Live-cell imaging reveals spatiotemporal dynamics of autophagosome formation and selective cargo recognition during nutrient starvation."
Secondary Focus Areas
Molecular Microbiology
- Prokaryotic gene regulation
- Bacterial cell biology
- Microbial metabolism pathways
- Host-pathogen molecular interactions
- Antimicrobial resistance mechanisms
Computational & Systems Biology
- Bioinformatics algorithms and tools
- Network biology and pathway analysis
- Molecular dynamics simulations
- Multi-omics data integration
- Predictive modeling of biological systems
Molecular Biotechnology
- Genome editing technologies (CRISPR systems)
- Synthetic biology and metabolic engineering
- Protein engineering and directed evolution
- Molecular biosensors and diagnostics
- Recombinant DNA technology
Molecular Biochemistry
- Metabolic pathways and regulation
- Lipid biochemistry and membrane biology
- Nucleic acid chemistry
- Enzyme kinetics and mechanisms
- Biomolecular thermodynamics
Molecular Immunology
- Immune receptor signaling
- Antigen recognition mechanisms
- Cytokine and chemokine biology
- Innate immunity molecular pathways
- Adaptive immune response regulation
Molecular Neuroscience
- Neurotransmitter synthesis and signaling
- Synaptic vesicle trafficking
- Ion channel structure and function
- Neuronal signal transduction
- Molecular basis of synaptic plasticity
Emerging Research Frontiers
Article Types & Editorial Priorities
Expedited Review (14-21 days)
- Original Research Articles (full-length studies)
- Systematic Reviews & Meta-Analyses
- Methods & Resources (novel techniques)
- Structural Biology Reports
Regular Review (28-35 days)
- Short Communications (rapid reports)
- Data Notes (datasets, protocols)
- Perspectives & Commentaries
- Technical Notes
Limited Acceptance
- Case Reports (only exceptional molecular insights)
- Opinion Pieces (by invitation only)
- Letters to Editor (post-publication discussion)
Editorial Standards & Requirements
Reporting Guidelines
All submissions must follow discipline-specific standards: ARRIVE (animal studies), MIQE (qPCR), MIAME (microarrays), or equivalent guidelines.
Data Availability
Raw data, code, and materials must be deposited in public repositories (GenBank, PDB, GitHub) with accession numbers provided at submission.
Ethics Compliance
Research involving human subjects, animals, or recombinant DNA requires institutional approval and ethics committee documentation.
Preprint Policy
Preprints on bioRxiv, arXiv, or similar servers are welcomed. Preprint DOI should be disclosed during submission.
Reproducibility
Detailed methods, reagent sources, statistical approaches, and experimental replicates must enable independent reproduction of findings.
Conflict of Interest
All authors must disclose financial, personal, or professional relationships that could influence the work.
